Transseptal approach utilizes the arterial system to access the left side of the heart.

• A. True
• B. False
• C. Requires imaging guidance
• D. Only during surgery

Answer: (B)

Transseptal access is about reaching the left heart from the right side by crossing the interatrial septum, and this is done via the venous system. In practice, catheters are introduced through a venous route—typically the femoral vein—into the right atrium, and then a puncture is made through the fossa ovalis to enter the left atrium. From there, mapping or ablation of left‑sided targets can be performed. This approach uses venous access rather than the arterial system. There are alternative left‑sided access methods that are arterial in nature (retrograde approaches), but the transseptal route itself specifically relies on the venous pathway to cross into the left heart. Imaging guidance is commonly used to visualize the septum and guide the puncture safely. Therefore, the statement is not correct.