In a patient with AVNRT, adenosine will have any effect on the tachycardia.

Study for the EPU Electrophysiology Exam with comprehensive questions and explanations. Enhance your knowledge with flashcards and a variety of question formats to ensure you are prepared to excel!

Multiple Choice

In a patient with AVNRT, adenosine will have any effect on the tachycardia.

Explanation:
AVNRT depends on conduction through the AV node for its reentrant circuit. Adenosine temporarily blocks AV nodal conduction by activating A1 receptors, which hyperpolarizes nodal cells and reduces calcium currents. This brief AV nodal block interrupts the reentrant loop, terminating the tachycardia. The effect occurs with standard doses and does not rely on unusually high doses. The presence of pre-excitation doesn’t prevent this termination, since the tachycardia mechanism in AVNRT is AV-nodal dependent; other tachycardias that use an accessory pathway might react differently, but AVNRT is typically terminated by adenosine.

AVNRT depends on conduction through the AV node for its reentrant circuit. Adenosine temporarily blocks AV nodal conduction by activating A1 receptors, which hyperpolarizes nodal cells and reduces calcium currents. This brief AV nodal block interrupts the reentrant loop, terminating the tachycardia. The effect occurs with standard doses and does not rely on unusually high doses. The presence of pre-excitation doesn’t prevent this termination, since the tachycardia mechanism in AVNRT is AV-nodal dependent; other tachycardias that use an accessory pathway might react differently, but AVNRT is typically terminated by adenosine.

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